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首页-小分子抑制剂&激动剂-GPCR-5-HT Receptor-S32212
S32212

Chemical Structure : S32212

CAS No.: 847871-78-7

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S32212 (S 32212)

货号: PC-22310Not For Human Use, Lab Use Only.

S32212 is a combined serotonin (5-HT)(2C) receptor inverse agonist and α(2)-adrenoceptor antagonist with pKi of8.2 (h5-HT2C), pKi of 7.2-8.2 for α(2A), α(2B) and α(2C).

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

S32212 is a combined serotonin (5-HT)(2C) receptor inverse agonist and α(2)-adrenoceptor antagonist with pKi of8.2 (h5-HT2C), pKi of 7.2-8.2 for α(2A), α(2B) and α(2C).

物理化学性质&存储条件

分子量 452.98
分子式 C25H29ClN4O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

1,2-Dihydro-N-[4-methoxy-3-(4-methyl-1-piperazinyl)phenyl]-3H-benz[e]indole-3-carboxamide hydrochloride

参考文献

1. Millan MJ, et al. J Pharmacol Exp Ther. 2012 Mar;340(3):750-64.

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