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首页-小分子抑制剂&激动剂-GPCR-Trace Amine-associated Receptor (TAAR)-S18616
S18616

Chemical Structure : S18616

CAS No.: 91561-41-6

S18616 (S 18616)

货号: PC-22309Not For Human Use, Lab Use Only.

S18616 is a potent, selective trace amine-associated receptor 1 (TAAR1) agonist with EC50 of 15 nM, also displayshigh affinity at native rat alpha(2)-adrenoceptor (AR) with pKi of 9.8.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

S18616 is a potent, selective trace amine-associated receptor 1 (TAAR1) agonist with EC50 of 15 nM, also displayshigh affinity at native rat alpha(2)-adrenoceptor (AR) with pKi of 9.8.

物理化学性质&存储条件

分子量 236.70
分子式 C12H13ClN2O
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(2S)-8-Chloro-3,4-dihydrospiro[naphthalene-2(1H),4′(5′H)-oxazol]-2′-amine

参考文献

1. Grossi G, et al. Molecules. 2024 Apr 11;29(8):1739.

2. Millan MJ, et al. J Pharmacol Exp Ther. 2000 Dec;295(3):1192-205.

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