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首页-小分子抑制剂&激动剂-Antibiotics and Antivirals-Influenza Virus-S119-8
S119-8

Chemical Structure : S119-8

CAS No.: 443639-96-1

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S119-8 (Influenza inhibitor S119-8)

货号: PC-35387Not For Human Use, Lab Use Only.

S119-8 (Influenza inhibitor S119-8) is a novel broad spectrum inhibitor of influenza virus replication (IC50=1.43 nM) by targeting the viral Nucleoprotein (NP), with no detectable cytotoxicity (CC50>50 uM).

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5 mg ￥780 In stock
10 mg ￥1180 In stock
25 mg ￥1980 In stock
50 mg ￥3280 In stock
100 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

S119-8 (Influenza inhibitor S119-8) is a novel broad spectrum inhibitor of influenza virus replication (IC50=1.43 nM) by targeting the viral Nucleoprotein (NP), with no detectable cytotoxicity (CC50>50 uM).
S119-8  also shows activity against multiple influenza B viruses and an oseltamivir-resistant influenza A virus, does not inhibit a non-influenza virus, VSV.
S119-8  exhibits synergistic combined with in vitro viral inhibition assays.

物理化学性质&存储条件

分子量 344.458
分子式 C23H24N2O
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

Benzamide, 4-(1,1-dimethylethyl)-N-[4-(phenylamino)phenyl]-

参考文献

1. White KM, et al. ACS Infect Dis. 2018 Feb 9;4(2):146-157.

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