S-Trityl-L-cysteine |CAS:2799-07-7 Probechem Biochemicals

Chemical Structure : S-Trityl-L-cysteine

CAS No.: 2799-07-7

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S-Trityl-L-cysteine (NSC 83265)

货号: PC-62340Not For Human Use, Lab Use Only.

S-Trityl-L-cysteine (NSC 83265) is a potent, cell-permeable, selective inhibitor of mitotic kinesin Eg5, inhibits basal ATPase activity (IC50=1 mM) and microtubule-activated ATPase activity of Eg5 (IC50=140 nM).

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100 mg	￥780	In stock
250 mg	￥1180	In stock
1 g		Get quote

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生物&药学活性

S-Trityl-L-cysteine (NSC 83265) is a potent, cell-permeable, selective inhibitor of mitotic kinesin Eg5, inhibits basal ATPase activity (IC50=1 mM) and microtubule-activated ATPase activity of Eg5 (IC50=140 nM).
S-Trityl-L-cysteine induces mitotic arrest in HeLa cells with an IC50 of 700 nM, and displays antitumor activity.

物理化学性质&存储条件

分子量	363.47
分子式	C22H21NO2S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	S-(Triphenylmethyl)-L-cysteine

参考文献

1. Brier S, et al. Biochemistry. 2004 Oct 19;43(41):13072-82.

2. DeBonis S, et al. Mol Cancer Ther. 2004 Sep;3(9):1079-90.

3. Zhao J, et al. Am J Cancer Res. 2014 Jan 15;4(1):42-52.

S-Trityl-L-cysteine (NSC 83265)

生物&药学活性

物理化学性质&存储条件

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S-Trityl-L-cysteine (NSC 83265)

生物&药学活性

物理化学性质&存储条件

参考文献

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