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首页-小分子抑制剂&激动剂-Others-Other Targets-S-C025
S-C025

Chemical Structure : S-C025

CAS No.: 2020058-34-6

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S-C025 (OXE-R antagonist S-C025)

货号: PC-35313Not For Human Use, Lab Use Only.

S-C025 is a highly potent antagonist of oxoeicosanoid receptor (OXE receptor, OXE-R) with IC50 of 0.12 nM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    S-C025 is a highly potent antagonist of oxoeicosanoid receptor (OXE receptor, OXE-R) with IC50 of 0.12 nM.
    S-C025 inhibits 5-oxo-ETE-induced calcium mobilization in human neutrophils.
    S-C025 is the highly potent OXE-R antagonists may provide a novel strategy for the treatment of eosinophilic disorders like asthma.

    物理化学性质&存储条件

    分子量 454.007
    分子式 C27H32ClNO3
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    (S)-5-(5-chloro-1-methyl-2-(6-phenylhexyl)-1H-indol-3-yl)-3-methyl-5-oxopentanoic acid

    参考文献

    1. Chourey S, et al. J Med Chem. 2018 Jul 4. doi: 10.1021/acs.jmedchem.8b00154.

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