S-230 | OXE receptor antagonist | Probechem Biochemicals

Chemical Structure : S-230

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S-230 (OXE receptor antagonist S-230)

货号: PC-35314Not For Human Use, Lab Use Only.

OXE-R antagonist S-230 is a highly potent antagonist of oxoeicosanoid receptor (OXE receptor) with IC50 of 0.12 nM, inhibits 5-oxo-ETE-induced calcium mobilization in human neutrophils.

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生物&药学活性

OXE-R antagonist S-230 is a highly potent antagonist of oxoeicosanoid receptor (OXE receptor) with IC50 of 0.12 nM, inhibits 5-oxo-ETE-induced calcium mobilization in human neutrophils.

物理化学性质&存储条件

分子量	377.909
分子式	C21H28ClNO3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(S)-5-(5-chloro-2-hexyl-1-methyl-1H-indol-3-yl)-3-methyl-5-oxopentanoic acid

参考文献

1. Cossette C, et al. J Med Chem. 2016 Nov 23;59(22):10127-10146.

2. Chourey S, et al. J Med Chem. 2018 Jul 4. doi: 10.1021/acs.jmedchem.8b00154.

S-230 (OXE receptor antagonist S-230)

生物&药学活性

物理化学性质&存储条件

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S-230 (OXE receptor antagonist S-230)

生物&药学活性

物理化学性质&存储条件

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