S-023-0996

Chemical Structure : S-023-0996

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货号: PC-27851Not For Human Use, Lab Use Only.

S-023-0996 is a potent, tumor cell selective, dual inhibitor of EZH2 and EGFR with IC50 of 2.41 nM and 42.18 nM respectively, inhibits tumor cell proliferation, migration and invasion in vitro with superior efficacy and safety than individual drug combinations.

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生物&药学活性

S-023-0996 is a potent, tumor cell selective, dual inhibitor of EZH2 and EGFR with IC50 of 2.41 nM and 42.18 nM respectively, inhibits tumor cell proliferation, migration and invasion in vitro with superior efficacy and safety than individual drug combinations.

物理化学性质&存储条件

分子量	857.07
分子式	C49H60N8O6
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-3-(ethyl(tetrahydro-2H-pyran-4-yl)amino)-5-((4-(2-(2-((4-((3-ethynylphenyl)amino)-7-methoxyquinazolin-6-yl)oxy)ethoxy)ethyl)piperazin-1-yl)methyl)-2-methylbenzamide

参考文献

1. Satrusal SR, et al. Mol Ther. 2026 Aug 25:S1525-0016(26)00715-X.

S-023-0996

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物理化学性质&存储条件

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S-023-0996

生物&药学活性

物理化学性质&存储条件

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