Ruxolitinib S enantiomer |CAS:941685-37-6 Probechem Biochemicals

Chemical Structure : Ruxolitinib S enantiomer

CAS No.: 941685-37-6

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货号: PC-45873Not For Human Use, Lab Use Only.

The chirality of Ruxolitinib (INCB-018424), which is a potent, selective, orally active JAK1/JAK2 inhibitor with IC50 of 3.3/2.8 nM, respectively..

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The chirality of Ruxolitinib (INCB-018424), which is a potent, selective, orally active JAK1/JAK2 inhibitor with IC50 of 3.3/2.8 nM, respectively.

分子量	306.365
分子式	C17H18N6
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	1H-Pyrazole-1-propanenitrile, β-cyclopentyl-4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-, (βS)-

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3. Verstovsek S, et al. N Engl J Med. 2010 Sep 16;363(12):1117-27.