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首页-小分子抑制剂&激动剂-JAK/STAT Signaling-JAK-Rovadicitinib
Rovadicitinib

Chemical Structure : Rovadicitinib

CAS No.: 1948242-59-8

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Rovadicitinib (TQ05105, TQ-05105)

货号: PC-25191Not For Human Use, Lab Use Only.

Rovadicitinib (TQ05105) is a potent, oral dual JAK1/2 and ROCK1/2 inhibitor targeting inflammatory and fibrotic components of chronic graft-versus-host disease (cGVHD).

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

Rovadicitinib (TQ05105) is a potent, oral dual JAK1/2 and ROCK1/2 inhibitor targeting inflammatory and fibrotic components of chronic graft-versus-host disease (cGVHD).

物理化学性质&存储条件

分子量 321.39
分子式 C17H19N7
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(R)-3-(3-amino-4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-3-cyclopentylpropanenitrile

参考文献

1. Zhao YM, et al. Blood. 2025 Jun 12;145(24):2857-2872.

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