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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-SGLT-Rongliflozin
Rongliflozin

Chemical Structure : Rongliflozin

CAS No.: 2035989-50-3

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Rongliflozin (Olorigliflozin, DJT1116PG)

货号: PC-24163Not For Human Use, Lab Use Only.

Rongliflozin (Olorigliflozin, DJT1116PG) is a potent, selective inhibitor of sodium-glucose co-transporter-2 (SGLT2), selectively inhibits renal glucose reabsorption, has an insulin-independent potential for type 2 diabetes mellitus.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

Rongliflozin (Olorigliflozin, DJT1116PG) is a potent, selective inhibitor of sodium-glucose co-transporter-2 (SGLT2), selectively inhibits renal glucose reabsorption, has an insulin-independent potential for type 2 diabetes mellitus.

物理化学性质&存储条件

分子量 450.91
分子式 C23H27ClO7
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(1R,2S,3S,4R,5S)-5-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-1-[(1R)-1-hydroxyethyl]-6,8-dioxabicyclo[3.2.1]octane-2,3,4-triol

参考文献

1. Zhang H, et al. Diabetes Obes Metab. 2020 Feb;22(2):191-202.

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