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首页-小分子抑制剂&激动剂-Nuclear Receptor/Transcription Factor-Eukaryotic Initiation Factor (eIF)-Rohinitib
Rohinitib

Chemical Structure : Rohinitib

CAS No.: 1139253-73-8

Rohinitib

货号: PC-72482Not For Human Use, Lab Use Only.

Rohinitib is a potent and specific inhibitor of eIF4A1, inhibits growth and survival of AML cells especially cells with FLT3-ITD.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    Rohinitib is a potent and specific inhibitor of eIF4A1, inhibits growth and survival of AML cells especially cells with FLT3-ITD.

    物理化学性质&存储条件

    分子量 521.56
    分子式 C29H31NO8
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20°C 12 个月; 4°C 6 个月
    配置液
    -80°C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    (1R,2R,3S,3aR,8bS)-1,8b-dihydroxy-N,N,6,8-tetramethoxy-3a-(4-methoxyphenyl)-3-phenyl-2,3,3a,8b-tetrahydro-1H-cyclopenta[b]benzofuran-2-carboxamide

    参考文献

    1. Nishida Y, et al. Leukemia. 2021 Sep;35(9):2469-2481.

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