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首页-小分子抑制剂&激动剂-Others-Other Targets-Rnaseh2c-In1
Rnaseh2c-In1

Chemical Structure : Rnaseh2c-In1

CAS No.: 1034736-09-8

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Rnaseh2c-In1

货号: PC-26574Not For Human Use, Lab Use Only.

Rnaseh2c-In1 is a specific small molecule inhibits of ribonuclease H2 subunit C (Rnaseh2c), significantly inhibits the proliferation of HCC via Cdk9 proliferation axis and CCL2/CCR2-mediated CD8+ Tex infiltration.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

Rnaseh2c-In1 is a specific small molecule inhibits of ribonuclease H2 subunit C (Rnaseh2c), significantly inhibits the proliferation of HCC via Cdk9 proliferation axis and CCL2/CCR2-mediated CD8+ Tex infiltration.

物理化学性质&存储条件

分子量 367.42
分子式 C19H17N3O3S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(R)-7-(3-hydroxy-4-methoxyphenyl)-2-(phenylamino)-6,7-dihydrothiazolo[4,5-b]pyridin-5(4H)-one

参考文献

1. Zengbin Wang, et al. J Immunother Cancer. 2026 Apr 15;14(4):e014993.

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