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首页-小分子抑制剂&激动剂-Tyrosine Kinase-FGFR-Risimtinib
Risimtinib

Chemical Structure : Risimtinib

CAS No.: 2126751-11-7

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Risimtinib

货号: PC-26354Not For Human Use, Lab Use Only.

Risimtinib (Compound 19a) is a highly potent FGFR inhibitor with IC50 of 2.1 nM against FGFR1, and 14.9 nM against the FGFR1-positive KG-1cancer cell.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

Risimtinib (Compound 19a) is a highly potent FGFR inhibitor with IC50 of 2.1 nM against FGFR1, and 14.9 nM against the FGFR1-positive KG-1cancer cell.

物理化学性质&存储条件

分子量 509.61
分子式 C30H31N5O3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

1-Naphthalenecarboxamide, 6-[[2-[[4-[(3R,5S)-3,5-dimethyl-1-piperazinyl]benzoyl]amino]-4-pyridinyl]oxy]-N-methyl-, rel-

参考文献

1. Manman Wei, et al. Eur J Med Chem. 2018 Jun 25:154:9-28.

2. Patent WO2017140269 A1 2017-08-24.

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