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首页-小分子抑制剂&激动剂-Others-SMN2 Modulator-Risdiplam
Risdiplam

Chemical Structure : Risdiplam

CAS No.: 1825352-65-5

Risdiplam (RG7916, RG-7916, RO7034067)

货号: PC-61397Not For Human Use, Lab Use Only.

Risdiplam (RG7916, RG-7916, RO7034067) is a highly potent, selective, orally active SMN2 splicing modifier for treatment of spinal muscular atrophy (SMA).

规格 价格 库存 数量
5 mg ¥1280 In stock
10 mg ¥1980 In stock
25 mg ¥3280 In stock
50 mg ¥5280 In stock
100 mg Get quote

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Risdiplam (RG7916, RG-7916, RO7034067) is a highly potent, selective, orally active SMN2 splicing modifier for treatment of spinal muscular atrophy (SMA).
RG7916 is undergoing clinical trials across the spectrum of spinal muscular atrophy, where it has shown promising early results.

物理化学性质&存储条件

分子量 401.474
分子式 C18H29N3O3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

7-(4,7-diazaspiro[2.5]octan-7-yl)-2-(2,8-dimethylimidazo[1,2-b]pyridazin-6-yl)-4H-pyrido[1,2-a]pyrimidin-4-one

参考文献

1. Mammas IN, et al. Exp Ther Med. 2018 Apr;15(4):3673-3679.

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