Rilapladib |Cas:412950-08-4 Buy Rilapladib from ProbeChem, Global Biochemicals Supplier

Chemical Structure : Rilapladib

CAS No.: 412950-08-4

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Rilapladib (SB-659032;SB 659032)

货号: PC-70212Not For Human Use, Lab Use Only.

Rilapladib (SB-659032, SB659032) is a potent, selective and oral lipoprotein-associated phospholipase A2 (Lp-PLA2) inhibitor with IC50 of 0.23 nM, for the treatment of Alzheimer's disease and atherosclerosis..

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10 mg	￥3980	In stock
25 mg	￥5980	In stock
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生物&药学活性

Rilapladib (SB-659032, SB659032) is a potent, selective and oral lipoprotein-associated phospholipase A2 (Lp-PLA2) inhibitor with IC50 of 0.23 nM.
Rilapladib (SB-659032, SB659032) shows potential for the treatment of Alzheimer's disease and atherosclerosis.

物理化学性质&存储条件

分子量	735.814
分子式	C40H38F5N3O3S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-(2-((2,3-difluorobenzyl)thio)-4-oxoquinolin-1(4H)-yl)-N-(1-(2-methoxyethyl)piperidin-4-yl)-N-((4'-(trifluoromethyl)-[1,1'-biphenyl]-4-yl)methyl)acetamide

参考文献

1. Tawakol A, et al. J Am Coll Cardiol. 2014 Jan 7-14;63(1):86-8.

2. Shaddinger BC, et al. PLoS One. 2014 Jan 27;9(1):e83094.

3. Wilensky RL, et al. Curr Opin Lipidol. 2009 Oct;20(5):415-20.

Rilapladib (SB-659032;SB 659032)

生物&药学活性

物理化学性质&存储条件

参考文献

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Rilapladib (SB-659032;SB 659032)

生物&药学活性

物理化学性质&存储条件

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