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Ribocil

Chemical Structure : Ribocil

CAS No.: 1381289-58-2

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Ribocil

货号: PC-45637Not For Human Use, Lab Use Only.

Ribocil is a synthetic mimic of riboflavin 5’-monophosphate (FMN) that competes with the natural ligand to inhibit FMN riboswitch-mediated expression of ribB.

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5 mg ￥1980 In stock
10 mg ￥3280 In stock
25 mg ￥5480 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Ribocil is a synthetic mimic of riboflavin 5’-monophosphate (FMN) that competes with the natural ligand to inhibit FMN riboswitch-mediated expression of ribB.
Ribocil depletes cellular levels of riboflavin with an IC50 value of 0.3 µM and inhibits E. coli growth with an MIC value of 2 ug/ml.

物理化学性质&存储条件

分子量 382.4826
分子式 C19H22N6OS
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

4(3H)-Pyrimidinone, 2-[1-[[2-(methylamino)-5-pyrimidinyl]methyl]-3-piperidinyl]-6-(2-thienyl)-

参考文献

1. Howe JA, et al. Nature. 2015 Oct 29;526(7575):672-7.

2. Hermann T. Nature. 2015 Oct 29;526(7575):650-1.

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