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首页-小分子抑制剂&激动剂-Cell Cycle/DNA Damage-Nucleoside Antimetabolite/Analog-Ribavirin
Ribavirin

Chemical Structure : Ribavirin

CAS No.: 36791-04-5

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Ribavirin (Tribavirin, Ribasphere)

货号: PC-28223Not For Human Use, Lab Use Only.

Ribavirin (Tribavirin, Ribasphere) is a synthetic guanosine analog with broad-spectrum of antiviral activity including HCV, HIV and RSV, inhibits the replication of RNA viruses such as flavi- and paramyxoviruses via inhibition of inosine monophosphate dehydrogenase enzyme (IMPDH), also inhibits viral RNA capping and the induces an error catastrophe.

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1 g ￥980 In stock
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生物&药学活性

Ribavirin (Tribavirin, Ribasphere) is a synthetic guanosine analog with broad-spectrum of antiviral activity including HCV, HIV and RSV, inhibits the replication of RNA viruses such as flavi- and paramyxoviruses via inhibition of inosine monophosphate dehydrogenase enzyme (IMPDH), also inhibits viral RNA capping and the induces an error catastrophe.

物理化学性质&存储条件

分子量 244.20
分子式 C8H12N4O5
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1H-1,2,4-triazole-3-carboxamide

参考文献

1. Ogbomo H, et al. Biochem Pharmacol. 2010 Jan 15;79(2):188-97.

2. Saito Y, et al. Bioorg Med Chem. 2003 Aug 15;11(17):3633-9.

3. Scheidel LM, et al. Virology. 1987 May;158(1):1-7.

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