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首页-小分子抑制剂&激动剂-Nuclear Receptor/Transcription Factor-Androgen Receptor (AR)-Rezvilutamide
Rezvilutamide

Chemical Structure : Rezvilutamide

CAS No.: 1572045-62-5

Rezvilutamide (SHR3680)

货号: PC-38370Not For Human Use, Lab Use Only.

Rezvilutamide (SHR3680) is a novel and pure androgen-receptor (AR) antagonist that shows potent antitumor activity against castration-resistant prostate cancer (CRPC) but with much less brain distribution than enzalutamide.

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5 mg ¥1980 In stock
10 mg ¥2980 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Rezvilutamide (SHR3680) is a novel and pure androgen-receptor (AR) antagonist that shows potent antitumor activity against castration-resistant prostate cancer (CRPC) but with much less brain distribution than enzalutamide.

物理化学性质&存储条件

分子量 479.474
分子式 C22H20F3N3O4S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(S)-4-(3-(4-(2,3-dihydroxypropoxy)phenyl)-4,4-dimethyl-5-oxo-2-thioxoimidazolidin-1-yl)-2-(trifluoromethyl)benzonitrile

参考文献

1. Xiaojian Qin, et al. BMC Med. 2022 Mar 4;20(1):84.

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