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首页-小分子抑制剂&激动剂-Nuclear Receptor/Transcription Factor-RAR/RXR-Retinoic acid
Retinoic acid

Chemical Structure : Retinoic acid

CAS No.: 302-79-4

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Retinoic acid (ATRA, Vitamin A acid, all-trans-Retinoic acid)

货号: PC-24819Not For Human Use, Lab Use Only.

Retinoic acid (ATRA) is a metabolite of vitamin A that plays important roles in cell growth, differentiation, and organogenesis, a natural agonist of RAR nuclear receptors with IC50s of 14 nM for RARα/β/γ. 

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500 mg ￥580 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Retinoic acid (ATRA) is a metabolite of vitamin A that plays important roles in cell growth, differentiation, and organogenesis, a natural agonist of RAR nuclear receptors with IC50s of 14 nM for RARα/β/γ. 

物理化学性质&存储条件

分子量 300.44
分子式 C20H28O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(2E,4E,6E,8E)-3,7-Dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoic acid

参考文献

1. Wu L, et al. PLoS One. 2016 Apr 14;11(4):e0153556.

2. Shaw N, et al. J Biol Chem. 2003 Oct 24;278(43):41589-92.

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