Chemical Structure : Retaspimycin hydrochloride
CAS No.: 857402-63-2
货号: PC-42456Not For Human Use, Lab Use Only.
Retaspimycin hydrochloride (IPI-504) is a derivative of 17-AAG and sepcific HSP90 inhibitor with EC50 of 119 nM.
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---|---|---|---|
5 mg | ¥1380 | In stock | |
10 mg | ¥2180 | In stock | |
25 mg | ¥3880 | In stock | |
50 mg | Get quote | ||
100 mg | Get quote |
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Retaspimycin hydrochloride (IPI-504) is a derivative of 17-AAG and sepcific HSP90 inhibitor with EC50 of 119 nM.
Retaspimycin hydrochloride (IPI-504) induces KIT degradation, tumor shrinkage, and cell proliferation arrest in xenograft models of gastrointestinal stromal tumors.
分子量 | 624.1652 | |
分子式 | C31H46ClN3O8 | |
外观性状 | Solid | |
储存条件 |
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Solubility |
DMSO: ≥ 56 mg/mL |
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Chemical Name/SMILES |
Geldanamycin, 18,21-didehydro-17-demethoxy-18,21-dideoxo-18,21-dihydroxy-17-(2-propen-1-ylamino)-, hydrochloride (1:1) |
1. Floris G, et al. Mol Cancer Ther. 2011 Oct;10(10):1897-908.
2. Hanson BE, et al. Expert Opin Investig Drugs. 2009 Sep;18(9):1375-83.
3. Oh WK, et al. Urology. 2011 Sep;78(3):626-30.
4. Siegel D, et al. Leuk Lymphoma. 2011 Dec;52(12):2308-15.
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