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Relatlimab

Chemical Structure : Relatlimab

CAS No.: 1673516-98-7

Relatlimab (Anti-human LAG3 mAb, human IgG4 (S228P)-Kappa; BMS-986016)

货号: PC-Ab1014Not For Human Use, Lab Use Only.

Relatlimab (BMS-986016) is a human IgG4 anti-LAG3 blocking mAb. Combination of LAG-3 with the immunomodulatory drug (IMiD) lenalidomide significantly increased IL-2 production by T cells and antibody-dependent cytotoxicity (ADCC) mediated by NK cells. These datas provide new insights into the potential anti-leukemic effects.

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1 mg ¥3580 In stock
5 mg ¥7580 In stock
10 mg ¥12800 In stock
100 mg Get quote

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Relatlimab (BMS-986016) is a human IgG4 anti-LAG3 blocking mAb. Combination of LAG-3 with the immunomodulatory drug (IMiD) lenalidomide significantly increased IL-2 production by T cells and antibody-dependent cytotoxicity (ADCC) mediated by NK cells. These datas provide new insights into the potential anti-leukemic effects

物理化学性质&存储条件

分子量
分子式 Human IgG4 (S228P)-Kappa
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

PBS, pH 7.0 Contains no stabilizers or preservatives

Chemical Name/SMILES

Relatlimab; BMS-986016; 1673516-98-7; Anti-Lymphocyte Activation Gene 3; Lag3 protein; Anti-human lymphocyte activation 3 protein; Anti-human LAG-3; Anti-human CD223

参考文献

1. 1, Christian Sordo-Bahamonde, et al. Cancers (Basel). 2021 Apr 27;13(9):2112. 2, Cancer Discov. 2021 Jul;11(7):1605-1606. 3, Yu X, et al. MAbs. 2019 Aug/Sep;11(6):1139-1148.

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