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Rebaudioside N

Chemical Structure : Rebaudioside N

CAS No.: 1220616-46-5

Rebaudioside N

货号: PC-26275Not For Human Use, Lab Use Only.

Rebaudioside N is a terpenoid glycoside isolated from the leaves of Stevia rebaudiana Bertoni, is a potent SH3 domain-binding kinase 2 (SBK2) agonist, effectively suppresses NLRP3-mediated IL-1β/IL-18 secretion, reduces inflammatory responses, and diminishes atherosclerotic burden.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Rebaudioside N is a terpenoid glycoside isolated from the leaves of Stevia rebaudiana Bertoni, is a potent SH3 domain-binding kinase 2 (SBK2) agonist, effectively suppresses NLRP3-mediated IL-1β/IL-18 secretion, reduces inflammatory responses, and diminishes atherosclerotic burden.

物理化学性质&存储条件

分子量 1275.30
分子式 C56H90O32
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(2S,3R,4S,5R,6R)-5-Hydroxy-6-(hydroxymethyl)-4-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-3-(((2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl (4R,4aS,6aR,9S,11aR,11bS)-9-(((2S,3R,4S,5R,6R)-5-hydroxy-6-(hydroxymethyl)-3,4-bis(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-4,11b-dimethyl-8-methylenetetradecahydro-6a,9-methanocyclohepta[a]naphthalen

参考文献

1. Schiffman SS, et al. Physiol Behav. 1994 Mar;55(3):547-59.

2. Ibrahim MA, et al. J Nat Prod. 2014 May 23;77(5):1231-5.

3. Cai L, et al. Eur Heart J. 2026 Feb 13:ehag047.

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