Ravidasvir dihydrochloride | HCV NS5A inhibitor | Probechem Biochemicals

Chemical Structure : Ravidasvir dihydrochloride

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Ravidasvir dihydrochloride (PPI-668, BI 238630)

货号: PC-61873Not For Human Use, Lab Use Only.

Ravidasvir (PPI-668, BI 238630) is a potent pan-genotypic HCV NS5A inhibitor with IC50 of 0.12/0.01/1.14 nM for HCV gt-1a/1b/3a in replicon luciferase assay.

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Ravidasvir (PPI-668, BI 238630) is a potent pan-genotypic HCV NS5A inhibitor with IC50 of 0.12/0.01/1.14 nM for HCV gt-1a/1b/3a in replicon luciferase assay.

Ravidasvir has been well tolerated and shown high sustained viral response rates as a key component in all-oral combination regimens in multiple human clinical trials.

物理化学性质&存储条件

分子量	835.83
分子式	C42H52Cl2N8O6
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Methyl N-[(2S)-1-{(2S)-2-[5-(6-{2-[(2S)-1-{(2S)-2-[(methoxycarbonyl)amino]-3-methylbutanoyl}pyrrolidin-2-yl]-1H-imidazol-4-yl}naphthalen-2-yl)-1H-benzimidazol-2-yl]pyrrolidin-1-yl}-3-methyl-1-oxobutan-2-yl]carbamate dihydrochloride

参考文献

1. Zhong M, et al. Bioorg Med Chem Lett. 2016 Sep 15;26(18):4508-12.

Ravidasvir dihydrochloride (PPI-668, BI 238630)

生物&药学活性

物理化学性质&存储条件

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Ravidasvir dihydrochloride (PPI-668, BI 238630)

生物&药学活性

物理化学性质&存储条件

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