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首页-新冠病毒相关-SARS-CoV-2 Inhibitors-Ratutrelvir
Ratutrelvir

Chemical Structure : Ratutrelvir

CAS No.: 2929236-94-0

Ratutrelvir (Travatrelvir, 83-0060, TRX01)

货号: PC-24173Not For Human Use, Lab Use Only.

Ratutrelvir (Travatrelvir, 83-0060, TRX01) is a potent, selective inhibitor of SARS-CoV-2 main protease Mpro (3CL protease).

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

Ratutrelvir (Travatrelvir, 83-0060, TRX01) is a potent, selective inhibitor of SARS-CoV-2 main protease Mpro (3CL protease).
Ratutrelvir has demonstrated in vitro activity against the original strain of the virus as well as the delta and omicron variants and is more active than nirmatrelvir in preclinical studies.

物理化学性质&存储条件

分子量 547.58
分子式 C27H32F3N5O4
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

3-Azabicyclo[3.1.0]hexane-2-carboxamide, N-[(1S)-1-cyano-2-(2,3-dihydro-2-oxo-1H-indol-3-yl)ethyl]-3-[(2S)-3,3-dimethyl-1-oxo-2-[(2,2,2-trifluoroacetyl)amino]butyl]-6,6-dimethyl-, (1R,2S,5S)-

参考文献

1. Patent WO2023245162 A2.

2. Patent WO2023093834 A1.

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