Rat C53 peptide

Chemical Structure : Rat C53 peptide

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货号: PC-72560Not For Human Use, Lab Use Only.

Rat C53 peptide (C53, pGC-B activator C53) is a novel potent, selective particulate guanylyl cyclase B (pGC-B) activator, activates pGC-B/cGMP signaling pathway, and enhances cGMP generating actions.

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生物&药学活性

Rat C53 peptide (C53, pGC-B activator C53) is a novel potent, selective particulate guanylyl cyclase B (pGC-B) activator, activates pGC-B/cGMP signaling pathway, and enhances cGMP generating actions.
C53 is highly resistant to NEP degradation and has less interaction with NPRC compared to CNP in vitro.
C53 activates the protective pGC-B/cGMP signaling pathway and possesses enhanced cGMP generating actions.
C53 inhibits fibroblast proliferation chronically and suppresses the differentiation of fibroblasts to myofibroblasts.

物理化学性质&存储条件

分子量
分子式
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 Month
Shipping
Solubility
Chemical Name/SMILES

参考文献

1. Yang Chen, et al. J Mol Cell Cardiol. 2019 May;130:140-150.

Rat C53 peptide

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物理化学性质&存储条件

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Rat C53 peptide

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物理化学性质&存储条件

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