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首页-小分子抑制剂&激动剂-GPCR-mGluR-Raseglurant hydrochloride
Raseglurant hydrochloride

Chemical Structure : Raseglurant hydrochloride

CAS No.:

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Raseglurant hydrochloride (ADX10059, ADX-10059)

货号: PC-27656Not For Human Use, Lab Use Only.

Raseglurant hydrochloride (ADX10059) is a selective metabotropic glutamate type 5 (mGlu5) receptor negative allosteric modulator (mGlu5 NAM), shows potential for treatment of neuropathic pain and migraine.

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25 mg ￥880 In stock
50 mg ￥1280 In stock
100 mg ￥1980 In stock
250 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Raseglurant hydrochloride (ADX10059) is a selective metabotropic glutamate type 5 (mGlu5) receptor negative allosteric modulator (mGlu5 NAM), shows potential for treatment of neuropathic pain and migraine.

物理化学性质&存储条件

分子量 276.74
分子式 C15H14ClFN2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

2-((3-Fluorophenyl)ethynyl)-4,6-dimethylpyridin-3-amine hydrochloride

参考文献

1. Font J, et al. Elife. 2017 Apr 11;6:e23545.

2. Romero-Fernandez W, et al. Mol Neurobiol. 2022 Oct;59(10):5955-5969.

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