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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-iGluR-Rapastinel
Rapastinel

Chemical Structure : Rapastinel

CAS No.: 117928-94-6

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Rapastinel (GLYX-13, Thr-Pro-Pro-Thr-NH2)

货号: PC-45064Not For Human Use, Lab Use Only.

Rapastinel (GLYX-13, Thr-Pro-Pro-Thr-NH2) is a tetrapeptide (TPPT-amide) that acts as a NMDA receptor glycine site partial agonist.

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5 mg ￥2280 In stock
10 mg ￥3680 In stock
25 mg ￥5880 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Rapastinel (GLYX-13, Thr-Pro-Pro-Thr-NH2) is a tetrapeptide (TPPT-amide) that acts as a NMDA receptor glycine site partial agonist.
Rapastinel readily crosses the blood-brain barrier and modulates the NMDA receptor.
Rapastinel shows potent cognitive-enhancing properties in a valid in vivo model of learning.

物理化学性质&存储条件

分子量 413.4686
分子式 C18H31N5O6
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

DMSO: ≥ 32 mg/mL
Chemical Name/SMILES

L-Threoninamide, L-threonyl-L-prolyl-L-prolyl-

参考文献

1. Moskal JR, et al. Neuropharmacology. 2005 Dec;49(7):1077-87.

2. Zhang XL, et al. Neuropharmacology. 2008 Dec;55(7):1238-50.

3. Burgdorf J, et al. Neurobiol Aging. 2011 Apr;32(4):698-706.

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