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首页-小分子抑制剂&激动剂-GPCR-Prostaglandin Receptor-Ramatroban
Ramatroban

Chemical Structure : Ramatroban

CAS No.: 116649-85-5

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Ramatroban (BAY u3405)

货号: PC-21315Not For Human Use, Lab Use Only.

Ramatroban (BAY u3405) is a potent selective thromboxane A2 (TxA2) antagonist with IC50 of 14 nM, also antagonizes CRTH2 (IC50=113 nM) by inhibiting PGD2 binding.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Ramatroban (BAY u3405) is a potent selective thromboxane A2 (TxA2) antagonist with IC50 of 14 nM, also antagonizes CRTH2 (IC50=113 nM) by inhibiting PGD2 binding.

物理化学性质&存储条件

分子量 416.47
分子式 C21H21FN2O4S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(R)-3-(3-(4-Fluorophenylsulfonamido)-3,4-dihydro-1H-carbazol-9(2H)-yl)propanoic acid

参考文献

1. Stearns BA, et al. Bioorg Med Chem Lett. 2009 Aug 15;19(16):4647-51.

2. Sugimoto H, et al. J Pharmacol Exp Ther. 2003 Apr;305(1):347-52.

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