Raclopride | Dopamine D2/D3 antagonist | Probechem Biochemicals

Chemical Structure : Raclopride

CAS No.: 84225-95-6

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Raclopride (FLA 870)

货号: PC-22235Not For Human Use, Lab Use Only.

Raclopride (FLA 870) is a potent, selective dopamine D2/D3 receptor antagonist, binds to D2 and D3 receptors with Ki of 1.8 nM and 3.5 nM, respectively.

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10 mg	￥780	In stock
25 mg	￥1180	In stock
50 mg	￥1880	In stock
100 mg	￥2980	In stock
250 mg		Get quote

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生物&药学活性

Raclopride (FLA 870) is a potent, selective dopamine D2/D3 receptor antagonist, binds to D2 and D3 receptors with Ki of 1.8 nM and 3.5 nM, respectively.
Raclopride (FLA 870) displays >150-fold selectivity over D1 and D4 receptors.
Raclopride (FLA 870) shows potential antipsychotic effects.

物理化学性质&存储条件

分子量	347.24
分子式	C15H20Cl2N2O3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(S)-3,5-dichloro-N-((1-ethylpyrrolidin-2-yl)methyl)-2-hydroxy-6-methoxybenzamide

参考文献

1. Köhler C, et al. Biochem Pharmacol. 1985 Jul 1;34(13):2251-9.

2. Farde L, et al. Proc Natl Acad Sci U S A. 1985 Jun;82(11):3863-7.

3. Seeman P, et al. Trends Pharmacol Sci. 1994 Jul;15(7):264-70.

Raclopride (FLA 870)

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物理化学性质&存储条件

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Raclopride (FLA 870)

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