RY796 | Probechem Biochemicals

Chemical Structure : RY796

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RY796 (RY 796;RY-796)

货号: PC-60669Not For Human Use, Lab Use Only.

A novel potent, selective Kv2 channel inhibitor that potently inhibits Kv2.1 and Kv2.2 with IC50 of 0.14 and 0.09 uM, respectively.

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1 g		Get quote

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生物&药学活性

RY796 is a potent, selective Kv2 channel inhibitor that potently inhibits Kv2.1 and Kv2.2 with IC50 of 0.14 and 0.09 uM, respectively.
RY796 shows no significant activity against Kv1.2 and Kv7.1, and Cav channels.
RY796 enhances GSIS in isolated wild-type (WT) mouse and human islets, but not in islets from Kv2.1(-/-) mice, enhances somatostatin release in isolated human and mouse islets.

物理化学性质&存储条件

分子量	353.466
分子式	C21H27N3O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(S)-2-(dimethylamino)-5-isobutyramido-N-(1-phenylethyl)benzamide

参考文献

1. Herrington J, et al. Mol Pharmacol. 2011 Dec;80(6):959-64.

2. Li XN, et al. J Pharmacol Exp Ther. 2013 Feb;344(2):407-16.

RY796 (RY 796;RY-796)

生物&药学活性

物理化学性质&存储条件

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RY796 (RY 796;RY-796)

生物&药学活性

物理化学性质&存储条件

参考文献

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