RX 871024 |CAS:142872-84-2 Probechem Biochemicals

Chemical Structure : RX 871024

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RX 871024 (RX871024;RX-871024)

货号: PC-60559Not For Human Use, Lab Use Only.

RX 871024 is an imidazoline compound that stimulate insulin release by inhibition of ATP-dependent K+ channels and inducing of Ca2+ mobilization in mouse pancreatic beta-cells.

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生物&药学活性

RX 871024 is an imidazoline compound that stimulate insulin release by inhibition of ATP-dependent K+ channels and inducing of Ca2+ mobilization in mouse pancreatic beta-cells.
RX 871024 blocks ATP-dependent K+ channels and membrane depolarization, and activates voltage-dependent Ca2+ channels.

物理化学性质&存储条件

分子量	297.78
分子式	C17H15N3 · HCl
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-(4,5-Dihydro-1H-imidazol-2-yl)-1-phenyl-1H-indole hydrochloride

参考文献

1. Efanova IB, et al. Diabetes. 1998 Feb;47(2):211-8.

2. Zaitsev SV, et al. Diabetes. 1996 Nov;45(11):1610-8.

3. Mourtada M, et al. Eur J Pharmacol. 1998 Jun 5;350(2-3):251-8.

4. Mourtada M, et al. Br J Pharmacol. 1999 Jul;127(5):1279-87.

RX 871024 (RX871024;RX-871024)

生物&药学活性

物理化学性质&存储条件

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RX 871024 (RX871024;RX-871024)

生物&药学活性

物理化学性质&存储条件

参考文献

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