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首页-小分子抑制剂&激动剂-Others-Other Targets-RU-NT-206
RU-NT-206

Chemical Structure : RU-NT-206

CAS No.: 1038304-09-4

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RU-NT-206

货号: PC-21807Not For Human Use, Lab Use Only.

RU-NT-206 is a small molecule inhibitor targeting the P-stalk binding pocket of ricin toxin A subunit (RTA) with IC50 of 7 uM, inhibits catalytic activity and protects cells against ricin and Stx2 holotoxins.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

RU-NT-206 is a small molecule inhibitor targeting the P-stalk binding pocket of ricin toxin A subunit (RTA) with IC50 of 7 uM, inhibits catalytic activity and protects cells against ricin and Stx2 holotoxins.

物理化学性质&存储条件

分子量 258.34
分子式 C15H14O2S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

5,5-dimethyl-4,5-dihydronaphtho[1,2-b]thiophene-2-carboxylic acid

参考文献

1. Michael J Rudolph, et al. Bioorg Med Chem. 2024 Feb 15:100:117614.

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