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首页-小分子抑制剂&激动剂-GPCR-Cannabinoid Receptor-RTICBM-229
RTICBM-229

Chemical Structure : RTICBM-229

CAS No.: 2250355-35-0

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RTICBM-229 (RTICBM229)

货号: PC-72729Not For Human Use, Lab Use Only.

RTICBM-229 is a potent, selective, brain-penetrant CB1 negative allosteric modulator (NAM) with IC50 of 169 nM in Ca2+ assay, 40 nM in GTPγS assay.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

RTICBM-229 is a potent, selective, brain-penetrant CB1 negative allosteric modulator (NAM) with IC50 of 169 nM in Ca2+ assay, 40 nM in GTPγS assay.

物理化学性质&存储条件

分子量 311.769
分子式 C17H14ClN3O
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

1-(3-(1H-pyrrol-2-yl)phenyl)-3-(4-chlorophenyl)urea

参考文献

1. Thuy Nguyen, et al. J Med Chem. 2019 Nov 14;62(21):9806-9823.

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