RTC-5 |CAS:1423077-49-9 Probechem Biochemicals

Chemical Structure : RTC-5

CAS No.: 1423077-49-9

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RTC-5 (PP2A activator RTC-5, TRC-382, TRC382)

货号: PC-62747Not For Human Use, Lab Use Only.

RTC-5 is a dual pathway inhibitor of PI3K-AKT and RAS-ERK signaling via putative activation of the tumor suppressor PP2A, exhibits GI50 of 12.6 uM against H1650 lung adenocarcinoma cells.

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10 mg	￥1480	In stock
25 mg	￥2580	In stock
50 mg	￥3980	In stock
100 mg		Get quote

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RTC-5 (PP2A activator RTC-5, TRC-382) is a dual pathway inhibitor of PI3K-AKT and RAS-ERK signaling via putative activation of the tumor suppressor PP2A, exhibits GI50 of 12.6 uM against H1650 lung adenocarcinoma cells.
RTC-5 (PP2A activator RTC-5, TRC-382) significantly decreases tumor growth in H1650 xenograft in mice.

物理化学性质&存储条件

分子量	510.956
分子式	C24H22ClF3N2O3S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(3-(3-chloro-10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)propyl)-4-(trifluoromethoxy)benzenesulfonamide

参考文献

1. Kastrinsky DB, et al. Bioorg Med Chem. 2015 Oct 1;23(19):6528-34.

RTC-5 (PP2A activator RTC-5, TRC-382, TRC382)

生物&药学活性

物理化学性质&存储条件

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RTC-5 (PP2A activator RTC-5, TRC-382, TRC382)

生物&药学活性

物理化学性质&存储条件

参考文献

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