RTC-30 |CAS:1423077-95-5 Probechem Biochemicals

Chemical Structure : RTC-30

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RTC-30 (RTC30)

货号: PC-62748Not For Human Use, Lab Use Only.

RTC-30 is an orally active, dual pathway inhibitor of PI3K-AKT and RAS-ERK signaling via putative activation of the tumor suppressor PP2A, exhibits GI50 of 15 uM against H1650 lung adenocarcinoma cells.

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生物&药学活性

RTC-30 is an orally active, dual pathway inhibitor of PI3K-AKT and RAS-ERK signaling via putative activation of the tumor suppressor PP2A, exhibits GI50 of 15 uM against H1650 lung adenocarcinoma cells.
RTC-30 significantly decrease tumor growth in H1650 xenograft in mice.

物理化学性质&存储条件

分子量	492.513
分子式	C24H23F3N2O4S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(R)-N-(3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-2-hydroxypropyl)-4-(trifluoromethoxy)benzenesulfonamide

参考文献

1. Kastrinsky DB, et al. Bioorg Med Chem. 2015 Oct 1;23(19):6528-34.

RTC-30 (RTC30)

生物&药学活性

物理化学性质&存储条件

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RTC-30 (RTC30)

生物&药学活性

物理化学性质&存储条件

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