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首页-小分子抑制剂&激动剂-GPCR-5-HT Receptor-RS67333 hydrochloride
RS67333 hydrochloride

Chemical Structure : RS67333 hydrochloride

CAS No.: 168986-60-5

RS67333 hydrochloride

货号: PC-23281Not For Human Use, Lab Use Only.

RS67333 hydrochloride is a potent and selective 5-HT4 receptor (5-HT4R) partial agonist with a pKi of 8.7 in guinea-pig striatum.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

RS67333 hydrochloride is a potent and selective 5-HT4 receptor (5-HT4R) partial agonist with a pKi of 8.7 in guinea-pig striatum.
RS67333 hydrochloride exhibits lower affinities at several other receptors including 5-HT1A, 5-HT1D, 5-HT2A, 5-HT2C, dopamine D1, D2 and muscarinic M1-M3 receptors.
RS67333 hydrochloride has neuroprotective effects.

物理化学性质&存储条件

分子量 389.36
分子式 C19H30Cl2N2O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

1-(4-Amino-5-chloro-2-methoxyphenyl)-3-(1-butylpiperidin-4-yl)propan-1-one hydrochloride

参考文献

1. R M Eglen, et al. 1995 Aug;115(8):1387-92.

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