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首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-Acetylcholinesterase (AChE)-ROS151
ROS151

Chemical Structure : ROS151

CAS No.:

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ROS151 (ROS-151)

货号: PC-27446Not For Human Use, Lab Use Only.

ROS151 is a potent acetylcholinesterase (AChE) inhibitor with IC50 of 14 nM (hAChE), as well as a chelator of Fe3+ and Cu2+, shows weak activity against eqBChE, hFAAH, hMAO-A and hMAO-B.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

ROS151 is a potent acetylcholinesterase (AChE) inhibitor with IC50 of 14 nM (hAChE), as well as a chelator of Fe3+ and Cu2+, shows weak activity against eqBChE, hFAAH, hMAO-A and hMAO-B.

物理化学性质&存储条件

分子量 391.36
分子式 C18H18FN3O6
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

3-((2-(5-Fluoro-2-nitrophenoxy)acetamido)methyl)phenyl dimethylcarbamate

参考文献

1. Leuci R, et al. Bioorg Chem. 2024 Dec;153:107895.

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