RO-8994 |CAS:1309684-94-3 Probechem Biochemicals

Chemical Structure : RO-8994

CAS No.: 1309684-94-3

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RO-8994 (RO8994)

货号: PC-45124Not For Human Use, Lab Use Only.

A highly potent and selective, small-molecule p53-MDM2 inhibitor with HRFT IC50 of 5 nM.

规格	价格	库存
10 mg	￥1380	In stock
25 mg	￥2280	In stock
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100 mg		Get quote

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生物&药学活性

RO-8994 (RO8994) is a highly potent and selective, small-molecule p53-MDM2 inhibitor with HRFT IC50 of 5 nM.
RO-8994 shows marked improvement in both in vitro and in vivo pharmacological properties.

物理化学性质&存储条件

分子量	613.5067
分子式	C31H31Cl2FN4O4
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	DMSO: ≥ 45 mg/mL
Chemical Name/SMILES	Spiro[3H-indole-3,3'-pyrrolidine]-5'-carboxamide, N-[4-(aminocarbonyl)-2-methoxyphenyl]-6-chloro-4'-(3-chloro-2-fluorophenyl)-2'-(2,2-dimethylpropyl)-1,2-dihydro-2-oxo-, (2'S,3R,4'S,5'R)-

参考文献

1. Zhang Z, et al. Bioorg Med Chem. 2014 Aug 1;22(15):4001-9.

2. Yu B, et al. Anticancer Agents Med Chem. 2016;16(10):1315-24.

RO-8994 (RO8994)

生物&药学活性

物理化学性质&存储条件

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RO-8994 (RO8994)

生物&药学活性

物理化学性质&存储条件

参考文献

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