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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-P2X Receptor-RO-51
RO-51

Chemical Structure : RO-51

CAS No.: 1050670-85-3

RO-51 (dual P2X(3)/P2X(2/3) antagonist)

货号: PC-62755Not For Human Use, Lab Use Only.

RO-51 is a potent, selective and drug-like dual P2X3 and P2X2/3 antagonist with pIC50 of 8.7 and 8.3, respectively.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    RO-51 is a potent, selective and drug-like dual P2X3 and P2X2/3 antagonist with pIC50 of 8.7 and 8.3, respectively.

    物理化学性质&存储条件

    分子量 474.299
    分子式 C17H23IN4O4
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    2-((4-amino-5-(5-iodo-2-isopropyl-4-methoxyphenoxy)pyrimidin-2-yl)amino)propane-1,3-diol

    参考文献

    1. Jahangir A, et al. Bioorg Med Chem Lett. 2009 Mar 15;19(6):1632-5.

    2. Serrano A, et al. J Neurosci. 2012 Aug 22;32(34):11890-6.

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