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首页-小分子抑制剂&激动剂-Cell Cycle/DNA Damage-RAD51-RI-2
RI-2

Chemical Structure : RI-2

CAS No.: 1417162-36-7

RI-2 (RAD51 inhibitor 2)

货号: PC-45083Not For Human Use, Lab Use Only.

RI-2 (RAD51 inhibitor 2) is a reversible RAD51 inhibitor with IC50 of 44 uM in the standard DNA binding assays.

规格 价格 库存 数量
5 mg ¥1880 In stock
10 mg ¥2980 In stock
25 mg ¥4880 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

RI-2 (RAD51 inhibitor 2) is a reversible RAD51 inhibitor with IC50 of 44 uM in the standard DNA binding assays.
RI-2 specifically inhibits HR repair in human cells, sensitize a broad range of immortalized human cells to mitomycin C.

物理化学性质&存储条件

分子量 433.2846
分子式 C21H18Cl2N2O4
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

DMSO: 15.5 mg/mL

Chemical Name/SMILES

1H-Pyrrole-2,5-dione, 1-(3,4-dichlorophenyl)-3-(4-methoxyphenyl)-4-(4-morpholinyl)-

参考文献

1. Budke B, et al. J Med Chem. 2013 Jan 10;56(1):254-63.

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