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首页-小分子抑制剂&激动剂-GPCR-Glucagon Receptor-RGT1383
RGT1383

Chemical Structure : RGT1383

CAS No.: 2428641-93-2

RGT1383 (RGT 1383)

货号: PC-20600Not For Human Use, Lab Use Only.

RGT1383 is a small molecule GLP-1R agonist, RGT1383 is a full agonist in G protein-mediated cAMP signaling with EC50 of 0.2 nM, and a partial agonist in β-arrestin-mediated signaling.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

RGT1383 is a small molecule GLP-1R agonist, RGT1383 is a full agonist in G protein-mediated cAMP signaling with EC50 of 0.2 nM, and a partial agonist in β-arrestin-mediated signaling.

物理化学性质&存储条件

分子量 554.58
分子式 C30H27FN6O4
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

O=C(C1=CC=C2C(N(C[C@H]3OCC3)C(CN4CC=C(C5=NC(OCC6=CC=C(C#N)C=C6F)=CC=C5)CC4)=N2)=N1)O

参考文献

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