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首页-小分子抑制剂&激动剂-Tyrosine Kinase-RET Tyrosine Kinase (c-RET)-RET agonist BT18
RET agonist BT18

Chemical Structure : RET agonist BT18

CAS No.: 924811-53-0

RET agonist BT18 (BT18)

货号: PC-49616Not For Human Use, Lab Use Only.

RET agonist BT18 is a small molecule allosteric agonist (ligand) of GDNF family receptor GFRα1 and RET receptor tyrosine kinase RetA function.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

RET agonist BT18 is a small molecule allosteric agonist (ligand) of GDNF family receptor GFRα1 and RET receptor tyrosine kinase RetA function.

物理化学性质&存储条件

分子量 637.65
分子式 C30H31F4N3O6S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(4-(5-((6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)sulfonyl)-2-methoxyphenyl)piperazin-1-yl)(4-fluoro-2-(trifluoromethyl)phenyl)methanone

参考文献

1. Larisa Ivanova, et al. ACS Omega. 2018 Sep 30;3(9):11407-11414.

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