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首页-小分子抑制剂&激动剂-GPCR-5-HT Receptor-RE104
RE104

Chemical Structure : RE104

CAS No.: 2756001-39-3

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RE104 (RE-104)

货号: PC-22530Not For Human Use, Lab Use Only.

RE104 is the prodrug of 4-OH-DiPT, a synthetic 5-hydroxytryptamine 2A receptor (5-HT2A receptor) agonist with Ki of 0.12 uM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

RE104 is the prodrug of 4-OH-DiPT, a synthetic 5-hydroxytryptamine 2A receptor (5-HT2A receptor) agonist with Ki of 0.12 uM.
A single dose of RE104 (1 mg/kg) significantly reduced mean immobility time at 1 week compared with vehicle (P < 0.001), confirming translational antidepressant potential.

物理化学性质&存储条件

分子量 374.48
分子式 C21H30N2O4
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

5-((3-(2-(diisopropylamino)ethyl)-1H-indol-4-yl)oxy)-5-oxopentanoic acid

参考文献

1. Bryson N, et al. ACS Chem Neurosci. 2024 May 17. doi: 10.1021/acschemneuro.4c00058.

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