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首页-小分子抑制剂&激动剂-Antibiotics and Antivirals-HIV-RDS1759
RDS1759

Chemical Structure : RDS1759

CAS No.: 1694628-20-0

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RDS1759

货号: PC-24020Not For Human Use, Lab Use Only.

RDS1759 is a specific small molecule inhibitor of HIV-1 RT-associated RNase H activity with IC50 of 8.6 uM (mutated HIV-1 RT R448A), inhibits viral inhibition rate with IC50 of 0.17 uM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

RDS1759 is a specific small molecule inhibitor of HIV-1 RT-associated RNase H activity with IC50 of 8.6 uM (mutated HIV-1 RT R448A), inhibits viral inhibition rate with IC50 of 0.17 uM.

物理化学性质&存储条件

分子量 359.81
分子式 C19H18ClNO4
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

Ethyl 6-[1-[(2-chlorophenyl)methyl]-1H-pyrrol-2-yl]-2,4-dioxo-5-hexenoate

参考文献

1. Corona A, et al. Antimicrob Agents Chemother. 2014 Oct;58(10):6101-10.

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