RBBP7 ligand Ynamide S9 intermidate

Chemical Structure : RBBP7 ligand Ynamide S9 intermidate

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货号: PC-24931Not For Human Use, Lab Use Only.

RBBP7 ligand Ynamide S9 intermidate is a novel covalent, electrophilic warhead and ligand of retinoblastoma binding protein 7 (RBBP7) E3 ligase, facilitating the development of PROTAC degraders targeting a wide range of proteins, including CDK4, PDE5, PI3K, AKT, BCR-ABL, BRD4, EGFRL858R, and EGFRL858R/T790M/C797S.

规格	价格	库存	数量
50 mg		Get quote
100 mg		Get quote
250 mg		Get quote

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生物&药学活性

物理化学性质&存储条件

分子量	395.59
分子式	C19H29NO4SSi
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	4-(N-methyl-N-((triisopropylsilyl)ethynyl)sulfamoyl)benzoic acid

参考文献

1. Liu Y, et al. Angew Chem Int Ed Engl. 2025 Jul 2:e202508538.