RBBP7-TP4 | RBBP7-H4 inhibitor | Probechem Biochemicals

Chemical Structure : RBBP7-TP4

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RBBP7-TP4 (Histone H4 (25-36))

货号: PC-28261Not For Human Use, Lab Use Only.

RBBP7-TP4 is a specific histone-binding protein RBBP7-targeting peptide with SPR KD of 0.204 uM, disrupts the RBBP7-histone H4 interaction, reduces histone H4 acetylation and downregulates DNMT1.

规格	价格	库存	数量
25 mg		Get quote
50 mg		Get quote
100 mg		Get quote

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生物&药学活性

RBBP7-TP4 is a specific histone-binding protein RBBP7-targeting peptide with SPR KD of 0.204 uM, disrupts the RBBP7-histone H4 interaction, reduces histone H4 acetylation and downregulates DNMT1.
RBBP7-TP4 inhibits the viability of JHH-7 cells.
inhibit the interaction between RBBP7 and histone H4.
RBBP7-TP4 exhibits potent anti-tumor activity in both cellular and xenograft mouse models of hepatocellular carcinoma (HCC).
RBBP7-TP4 synergizes with HDAC inhibitors to enhance epigenetic efficacy in HCC models.

物理化学性质&存储条件

分子量	1366.64
分子式	C59H107N21O16
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Asn-Ile-Gln-Gly-Ile-Thr-Lys-Pro-Ala-Ile-Arg-Arg

参考文献

1. Zan Gao, et al. Cell Chem Biol. 2026 Sep 15:S2451-9456(26)00322-3.

RBBP7-TP4 (Histone H4 (25-36))

生物&药学活性

物理化学性质&存储条件

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RBBP7-TP4 (Histone H4 (25-36))

生物&药学活性

物理化学性质&存储条件

参考文献

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