RB-101 |CAS:135949-60-9 Probechem Biochemicals

Chemical Structure : RB-101

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RB-101 (RB101)

货号: PC-63049Not For Human Use, Lab Use Only.

RB-101 is an mixed enkephalinase inhibitor that inhibits Aminopeptidase N and Neutral Endopeptidase with IC50 of 11 nM and 2 nM, respectively.

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生物&药学活性

RB-101 is an mixed enkephalinase inhibitor that inhibits Aminopeptidase N and Neutral Endopeptidase with IC50 of 11 nM and 2 nM, respectively; induces potent analgesic responses in mice and rats.

物理化学性质&存储条件

分子量	582.84
分子式	C31H38N2O3S3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Phenylmethyl (2S)-2-[(2-([(2S)-2-amino-4-methylsulfanylbutyl]disulfanylmethyl)-3-phenylpropanoyl)amino]-3-phenylpropanoate

参考文献

1. Ruiz-Gayo M, et al. Brain Res. 1992 Feb 7;571(2):306-12.

2. Noble F, et al. J Pharmacol Exp Ther. 1992 Apr;261(1):181-90.

3. Baamonde A, et al. Eur J Pharmacol. 1992 Jun 5;216(2):157-66.

4. Fournié-Zaluski MC, et al. J Med Chem. 1992 Jun 26;35(13):2473-81.

RB-101 (RB101)

生物&药学活性

物理化学性质&存储条件

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RB-101 (RB101)

生物&药学活性

物理化学性质&存储条件

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