R-huezole

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Chemical Structure : R-huezole

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货号: PC-47072Not For Human Use, Lab Use Only.

R-huezole is a phase-separating small molecule that forms liquid droplets to selectively sequester tubulin, enters cultured human cells and prevents cell mitosis by forming tubulin-concentrating condensates in cells.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

R-huezole is a phase-separating small molecule that forms liquid droplets to selectively sequester tubulin, enters cultured human cells and prevents cell mitosis by forming tubulin-concentrating condensates in cells.

物理化学性质&存储条件

分子量	641.798
分子式	C34H42F3N5O2S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(R)-5-((5-benzyl-4-(3-(trifluoromethyl)phenyl)-4H-1,2,4-triazol-3-yl)thio)-1-(4-(3-cyclopentylpropanoyl)-3-methylpiperazin-1-yl)pentan-1-one

参考文献

1. Genyir Ado, et al. Chem Sci. 2022 Apr 20;13(19):5760-5766.

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