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首页-小分子抑制剂&激动剂-Wnt/Notch/Hedgehog-Beta-catenin-R-999636
R-999636

Chemical Structure : R-999636

CAS No.: 90833-53-7

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R-999636 (R999636)

货号: PC-61806Not For Human Use, Lab Use Only.

R-999636 is a small molecule inhibitor that effectively inhibits the β-catenin/Tcf4 interaction with Ki of 8.8 uM in FP assay.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    R-999636 is a small molecule inhibitor that effectively inhibits the β-catenin/Tcf4 interaction with Ki of 8.8 uM in FP assay.
    R-999636 displays 5.8-fold and 7.8-fold selectivity over β-catenin/E-cadherin and β-catenin/APC interactions, respectively.

    物理化学性质&存储条件

    分子量 395.239
    分子式 C21H12Cl2N2O2
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    2,3-bis(4-chlorophenyl)quinoxaline-6-carboxylic acid

    参考文献

    1. Zhang M, et al. ACS Med Chem Lett. 2013 Jan 8;4(2):306-11.

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