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首页-小分子抑制剂&激动剂-Others-Other Targets-R-55
R-55

Chemical Structure : R-55

CAS No.: 2076-91-7

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R-55 (R 55;R55)

货号: PC-70004Not For Human Use, Lab Use Only.

A small molecule that stabilizes Retromer against thermal denaturation.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

A small molecule that stabilizes Retromer against thermal denaturation; increases the levels of retromer proteins, shifts APP away from the endosome, and decreases the pathogenic processing of APP; has potential therapeutic implications for neurodegenerative diseases.

物理化学性质&存储条件

分子量 260.392
分子式 C8H12N4S3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

thiophene-2,5-diylbis(methylene) dicarbamimidothioate

参考文献

1. Mecozzi VJ, et al. Nat Chem Biol. 2014 Jun;10(6):443-9.

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